In some of our models of detox pads contains the ingredient chitosan.  This ingredient not recommended for people that are highly sensitivity to shellfish (seafood allergies). Although chitosan is very beneficial for detox, people with high sensitivity to shellfish should use our detox pads without chitosan. The Grapefruit SS1Li, Enhanced Grapefruit TG-1i, Quick QU-1, Silver AGI, and Green Tea CCI editions do not contain the chitosan ingredient.